NEW SITE ----> Go to http://www.miketnelson.com < -----for all my latest info a this site below is from about 5-8 years ago. Michael T Nelson, MS CSCS, RKC is a PhD Candidate in Kinesiology (Exercise Physiology) at the U of MN and Fitness Consultant in White Bear Lake, MN. Ramblings here about research, training, nutrition, exercise phys, Z Health, joint mobility, and whatever else I want
Saturday, November 29, 2008
They Got Next: Specialization?
I need to thank Cal Dietz here at the U of MN for sending this on, as he got it from Larry. It was written by Laura Ulrich who is a contributing writer for Athletic Management.
Very cool article on specialization. Let's hope the tide is turning and to all in the fitness/training profession it is our job to help facilitate this change now! Enjoy
Mike N
They Got Next
When next season means another sport, and not the start of club, the multi-sport message is getting through. But how do you do it? The keys are offering incentives to athletes and convincing arguments to parents.
By Laura Ulrich
Laura Ulrich is a contributing writer for Athletic Management. She can be reached at: laura@MomentumMedia.com.
When soccer coach Tim Twellman looks over his new team on the first day of practice every year, it doesn't take him long to spot the players who specialize in the sport. It's not their skill level that sets them apart, however. The players who compete in other sports are eager and enthusiastic, wide-eyed and ready to put a ball to their feet. The year-round soccer players are asking what time practice ends.
"By the time they get to me, they're tired of soccer," says Twellman, Head Girls' Soccer Coach at Villa Duchesne High School in St. Louis. "Just when they should really be getting excited, they're pretty much done with the sport. The best athletes I get are the ones who play other sports. When soccer season rolls around, they can't wait to play."
Dr. Joel Brenner sees the same thing. Director of Sports Medicine and Adolescent Medicine at the Children's Hospital of the King's Daughters, in Norfolk, Va., Brenner treats high school athletes for overuse injuries that used to be reserved for much older athletes. But Brenner says strains, pulls, and stress fractures are only the most visible manifestation of why early sport specialization is a bad idea—the adolescents he treats are often psychologically burned out on their sport as well.
"It's easy to see that something's going wrong when they're limping or holding their arm, but burnout is harder to spot," Brenner says. "I've had 15-year-old kids tell me they no longer enjoy anything about their sport, but they're doing it because they know their coaches and parents expect them to."
For the past decade, athletic administrators have watched and winced as sport specialization has wreaked havoc on educational athletics. Faced with the proliferation of club teams and parents' obsession with college athletic scholarships, athletic directors have often felt helpless in thwarting the trend. Although they have sounded the alarms, administrators have struggled to find allies in the fight against specialization.
But finally, that seems to be changing. With more and more sports medicine specialists calling for a halt to sport specialization, college coaches publicly stating that they are looking for multi-sport athletes as they recruit, and high school coaches realizing that one-sport athletes don't make the best players, the tide appears to be turning. Which is why athletic directors are starting a new charge against sport specialization.
APPEAL TO ATHLETES
Up to this point, most attempts to encourage multi-sport participation have been indirect and ineffective. Simply encouraging the star basketball player to put his long arms and legs to use as a wide receiver or asking the softball slugger to forego her fall club team and join the field hockey squad have fallen on deaf ears. Telling parents that multi-sport participation has many benefits is returned with a blank stare.
But what is working is an approach that appeals to athletes directly. Its two main prongs are getting coaches on board and offering real rewards for playing multiple sports at one's high school.
Tim Brown, Athletic Director at Mt. Anthony Union High School in Bennington, Vt., says a key is to educate coaches on how so much of what they do can give the right or wrong message. "For example, a huge problem is when a coach coaches a club team in the off-season and his or her high school players get the message that they need to play in the off-season to make the high school team, become a starter, or get playing time," he says.
Coaches who emphasize off-season conditioning can also keep an athlete from electing to play another sport. "When a high school football player's coach tells him, 'You could be the best player on the team next year if you spend the off-season conditioning,' that player is going to wind up in the weightroom instead of playing basketball," Twellman says.
To ensure her coaches aren't relaying these types of messages to their athletes, Dory Smith, Athletic Director at Villa Duchesne, keeps the multi-sport message at the front of her coaches' minds. She emphasizes it in her department's philosophy statement, includes the topic as an agenda item at coaches meetings, and regularly talks about it one-on-one with her staff.
"I make sure my coaches know I expect them to be educators and that their first job is to teach life lessons, not win games," she says. "Coaches are competitive, and it's easy for them to start thinking, 'If I could just get this player to work a little more in the off-season, we could win district next year.' They need to be reminded of our department philosophy on multi-sport participation often to counteract that kind of thinking."
Smith then works to stay aware of the messages her coaches are sending by paying attention to what kids and parents say. "Sometimes I'll find coaches saying, 'Multi-sport participation is great,' but then contradicting that with what they're actually asking kids to do," she says. "I've had to tell some coaches, 'You're sending mixed messages, and it needs to stop.'"
The issue is important enough to Smith that she makes it one of the major aspects of the hiring process. "In an interview, I'm very clear about our multi-sport philosophy, and I look to hire coaches who have an overall sense of perspective and balance," she says. "I also bring other coaches in on interviews so they can assess whether they think the candidate will fit into our system and promote playing on other teams. If I find a coach who is fantastic otherwise but doesn't buy into our multi-sport philosophy, I keep looking."
While reaching athletes through their coaches is the first step, offering incentives is also key. At Villa Duchesne, Smith makes sure multi-sport athletes get a special mention in the school newsletter and she recognizes them at the annual athletic banquet. In addition, athletes who play three sports for four years are honored with a medal and a plaque in the school's trophy area.
Kevin Kuntz, Athletic Director at The Stony Brook (N.Y.) School, oversees an incentive program for multi-sport athletes called the "Bear Blanket Award." It awards points for each season an athlete participates in, and athletes who earn 12 points receive a large blanket with a bear head on it, representing the school's mascot.
"We award half a point for a j.v. letter, a full point for a varsity letter, and a full point for a postseason honor," Kuntz says. "It's practically impossible to tally 12 points unless you play multiple sports.
"The program is definitely working," he continues. "Kids keep track of their points, and quite often one of them will tell me, 'I wasn't going to go out for a sport this season, but if I don't, I won't earn my blanket.'"
Last year, four athletes earned bear blankets. "One of them played six different sports in his five years here," Kuntz says. "That's what I like about this program—it encourages kids to try different things and experiment, which is what they should be doing at this age."
At Mt. Anthony, Brown also recognizes multi-sport athletes with a special award. The "Tri-Honor Athlete" program rewards student-athletes who go multi-sport while also achieving academically. Each year, athletes who play a sport in all three seasons (or serve as a statistician or team manager) and also make the honor roll in all three seasons are named Tri-Honor Athletes and receive a pin to go on their varsity letter. A large plaque in the cafeteria lists the names of each Tri-Honor Athlete by year.
"Kids love the pins, but the plaque is what really seems to motivate them," Brown says. "It's a very public, permanent recognition."
When Brown instituted the program in 1989, 12 athletes out of a student enrollment of 1,300 were named. In 2008, 53 athletes earned the award. "It's grown every year," he says. "What's great is that I can track the numbers and show parents that we're really making a difference."
To further encourage participation, Brown does all he can to help athletes find a place, in part by offering as many no-cut teams as possible. "It really helps to give kids options where they know they can make the team," Brown says. "At our school, track, cross country, and tennis have no cuts, and we try to keep cuts to a minimum in all of our other sports, too."
EDUCATING PARENTS
Getting coaches and athletes on board is doable. But parents are a much tougher nut to crack. They want what they think is best for their son or daughter and can't always see the forest through the trees. Oftentimes their views are skewed by the number of children who specialize. They see the neighbor's kid practicing year-round and worry they might be failing their child if they don't provide the same opportunity.
As Adam Naylor, Director of the Athletic Enhancement Center at Boston University and a sports psychologist, explains, "Parents have to cope with the 'everybody's doing it' mentality," he says. "It takes a lot of confidence to go against the trend and say, 'My kid is going to be just fine.'
"That confidence comes from having the facts, so we can't just tell parents, 'Specialization is bad.' We have to tell them why," he continues. "We need to give them facts to support their choice by discussing overuse and burnout and showing them that multi-sport athletes can be even more successful athletically than those who specialize."
When talking to parents about the topic, the more specifics you can offer, the more your words will resonate. What athletic directors and experts have found sinks in deepest are examples of how sport specialization does not correlate with future athletic success.
"The way I explain it to parents is that the earlier you specialize, the earlier you peak," Naylor says. "The athlete who plays one sport at age 12 is likely to peak at age 16—the opposite of what you want if you're trying to get to the next level. Athletes who specialize later peak later and they reach a much higher level of play."
"You get a lot of athletic development by doing several different sports when you're young," Brenner says. "Developing overall conditioning, balance, and coordination through multiple sports ultimately makes a far better athlete than only using your body in one way."
Brown likes to give parents examples of multi-sport athletes who have successfully gone on to college or the pros. "A few years back, we had an athlete from our school go on to the WNBA," he says. "She played soccer, basketball, and softball for us. I always use her as an example, as well as other athletes whose stories I can find."
Parents will also open their ears to information about college scholarships, and they need to be educated about two things: the long odds of their child getting the kind of scholarship they're envisioning, and the fact that college coaches generally find Division I-caliber athletes no matter where they are, so playing year round for an expensive club is not necessary. They also need to know that more and more college coaches are going on record saying they want multi-sport athletes, not ones who only play their sport.
Jack Parker, Head Men's Ice Hockey Coach at Boston University, says he is starting to recruit more athletes from out-of-state instead of Massachusetts high school and club stars who play hockey almost year round. "By the time I see these kids, they are bored, burned out, and often injured," he says. "There are more players ready to play college hockey in California and Texas right now than in Massachusetts because they don't play it year round. Specialization is killing hockey in our state."
University of Northern Colorado Head Wrestling Coach Jack Maughan has similar feelings about sport specialization and now recruits multi-sport athletes as much as possible. "Wrestling is so life-consuming," Maughan told the Greeley (Colo.) Tribune. "Sometimes when they get here they are burned out. The goal is to get to college and then that's it. If they have done it all of their lives and they still have that hunger, then sure I'd recruit them. But that's not always the case."
Few things will get a parent's attention quicker than risks to their child's health. Thus, facts about injuries are also important to provide. In an article he wrote for Pediatrics last year, Brenner explained that young athletes who perform the motions of their sport over and over without a break—often before they have perfected the proper mechanics—are at risk for injuries to bones, muscles, and tendons. In fact, research indicates that half of all injuries seen by pediatric sports medicine doctors today are related to overuse.
"Each sport has particular injuries that we see over and over in kids who play year round," Brenner says. "We see runners and field hockey players with stress fractures of the tibia in the lower leg, baseball pitchers with stress fractures in the upper arm, and gymnasts with stress fractures in the spine. Tendonitis is common in swimmers and baseball, volleyball, and basketball players."
At best, overuse injuries sideline players temporarily. At worst, they can end a career. "It depends on how early the athlete comes in and how well they adhere to the treatment plan," Brenner says. "I've seen cases where kids ended up with chronic pain."
As many coaches and administrators have seen, the risks aren't only physical. Athletes who specialize are vulnerable to burnout. Parents may have a hard time believing that their child may tire of a sport they love, so Naylor uses an analogy to help them understand how it can happen.
"I compare it to what would happen if you ate your favorite dinner every night for six months," Naylor says. "'You might love it to begin with, but by the end, you'd never want to see it again.' The same is true for kids who play too much of one sport.
"I've had high school athletes who play their sport year round tell me, 'I don't even know why I play anymore,'" he continues. "Kids who specialize often end up leaving their sport a lot earlier than those who play multiple sports."
ACCENTUATE THE POSITIVE
Along with talking to parents about the risks of sport specialization, it's crucial to explain the huge benefits of multi-sport participation. One big selling point is that athletes who play multiple sports get to experience different roles on different teams.
"They might be the star hockey player, but they're the backup third baseman on the baseball team," Parker says. "When they get to college and suddenly they're not the star on my team, they already know how to handle that. It makes them a better teammate."
Kuntz emphasizes that these kinds of learning experiences offer payoffs far beyond the athletic arena. "Playing a sport they're not so good at is often where the most personal growth takes place," he says. "When they're out in the job world, they've experienced being the leader but also taking direction and digging in when they're not in a leadership role."
Experiencing coaches with different styles also helps athletes grow. "Learning to work hard for different types of coaches will benefit them later," Smith says. "It correlates directly to being able to work for different types of bosses."
Another key piece of the discussion involves helping parents see that the high school sports experience is inherently different than the club sport experience. "When a student plays a high school sport in each season, they're on a team that has to comply with academic standards, training rules, and eligibility rules, and they usually have a coach who is an educator," Brown says. "They're also staying connected to their school and that connection helps them stay motivated. These are all huge advantages over having a child go off and play a club sport year round. It's important to make sure parents understand the difference."
Brown illustrates the point with some impressive figures. "I keep track of our honor roll numbers," he says. "Last year, 45 percent of our one-sport athletes made the honor roll. Fifty-nine percent of our two-sport athletes made the honor roll, and 81 percent of our three-sport athletes made the honor roll. Playing multiple school sports is a pretty easy sell once parents hear those numbers."
LIVING WITH CLUBS
Any plan to encourage multi-sport participation would not be complete without discussing conflicts with club sports. "It's difficult, because some kids are going to make the choice to play club, and if they also want to compete on multiple high school teams, the seasons are going to overlap," says Smith. "You don't want to discourage them from playing an additional sport at your school, but at the same time, you can't have athletes missing high school games and practices for club events."
Naylor believes athletic directors who look for ways to accommodate club participation without compromising their high school teams are on the right track. "We aren't going to get rid of the club sports phenomenon anytime soon," he says. "We need to get beyond the turf battles and find ways to work together."
Kuntz encourages his coaches to allow their players a little latitude. "We're clear that if it's a contest, the athletes' obligation is to the high school sport," he says. "But we work with them when it comes to missing practices. I feel that if an athlete plays fall soccer for us and runs track for us in the spring, but misses two track practices out of 60 in order to attend a club soccer tournament, that's a pretty easy compromise. They're still getting the multi-sport experience. However, if the coach is not okay with a player missing practice, I always back the coach."
The next step, Naylor believes, is a lot more discussion between club and high school sports. "It really needs to start with everyone sitting down and asking, 'What is the objective of kids playing sports?'" he says. "'Why are we all doing this?' Ultimately, club and high school people may need to agree to disagree, but still find ways to collaborate and support each other so the system is better for kids. The goal is to stop pulling kids in two different directions and undermining each other."
In the end, dialogue among all parties—administrators, coaches, athletes, and parents—is the key to reversing the trend of sport specialization. "I think we're at a point where more coaches and administrators understand the downsides of specialization, but the understanding can't stop there," Naylor says. "It's really important to keep this issue on the front burner and to continue talking to parents and kids."
"There's no question that middle school and high school athletes benefit from playing multiple sports," Brenner says. "The challenge continues to be getting that message across to athletes and parents in a convincing way."
Sidebar: TIME TO TALK
When and how can you get parents to hear your message about sport specialization? Dory Smith, Athletic Director at Villa Duchesne High School in St. Louis, has found that her department's preseason parents meetings offer a great opportunity. "We have one big meeting in the fall for parents of all athletes, and I always bring this issue up," she says. "I've learned that examples get through to parents better than anything else, so I tell them success stories about our multi-sport athletes."
Letting parents hear from an expert can also help. Adam Naylor, Director of the Athletic Enhancement Center at Boston University and a sports psychologist, suggests bringing in a sports psychologist, athletic trainer, sports medicine physician, college coach, or college athlete. "Your special speaker will probably be saying the same thing you are, but they may make a bigger impact," he says.
Ideally, athletic directors can also get the message out to parents of younger athletes, when sport specialization is really kicking in. "I talk about it at the beginning-of-the-year meeting with our middle school parents and I also send a letter home about it," says Tim Brown, Athletic Director at Mt. Anthony Union High School in Bennington, Vt. "This is usually their first experience with interscholastic sports, so it's a great opportunity to put the emphasis on experience, life skills, and participation—and make sure it stays there."
And sometimes, parents just need someone to tell them that all the talk about sport specialization they hear from other parents is not gospel. "For every parent who envisions their child as a professional athlete and wants them to play their sport 12 months a year, there are a lot of parents who just want their child to enjoy the experience and who would love to feel better about that choice," Brown says. "Our job is to communicate the message to the majority early, while they are still open to hearing a different philosophy."
Sidebar: ONE PASSION
Athletic directors attempting to encourage multi-sport participation are often hit with a tough question from parents: "My child is passionate about his sport and playing it year-round is what he wants. What's wrong with that?"
"There's nothing wrong with being passionate about something—it's a great thing," says Adam Naylor, Director of the Athletic Enhancement Center at Boston University and a sports psychologist. "But just because a child loves something doesn't mean it's healthy to give them as much of it as they want. Parents need help understanding that kids aren't always the best judges of what's best for themselves."
When Naylor encounters a child who is driven about a sport, he urges parents to help them channel that drive into different activities to avoid overuse and burnout. "I tell them, 'Get your child to take a break and sign up for something different,'" he says. "Nine times out of 10, they'll love the new sport two weeks into it. And when they go back to their primary sport, they'll love it even more. By helping their child diversify, they're actually preserving that passion."
Dory Smith, Athletic Director at Villa Duchesne High School in St. Louis, tells parents this story. "A tennis player I know stopped playing basketball early in high school to concentrate on tennis," she says. "He went on to play tennis at an NCAA Division III school, and by his junior year, he went to his mother and said, 'Why did you ever let me quit basketball?' She said, 'You were the one who wanted to do tennis all the time. You wanted to be at the club by 5 a.m.' And he responded, 'I was too young to know what I wanted. Now I really regret missing out on high school basketball.'
"This is not uncommon," Smith continues. "I was at a conference recently where a panel of athletes shared their experiences as one-sport athletes and all of them talked about wishing they had played on more high school teams instead. Once parents hear that, they realize it's their job to see the big picture, even if their child thinks they want to eat, breathe, and sleep one sport year round."
Tim Twellman, Head Girls' Soccer Coach at Villa Duchesne, urges parents to discuss the issue honestly with their child. "Is it really the child who wants to play year-round?" he asks. "When was the last time the parents asked the child what he or she really wants and if he or she is really having fun? If they ask the question and make it clear that any answer is okay, they are likely to find out their child just wants some time to relax and be with their friends, but that they feel a lot of pressure to please the adults in their life."
Twellman is speaking not just from a coach's perspective. All three of his children earned NCAA Division I soccer scholarships and one son now plays professional soccer. Still, when they were young, Twellman practiced what he now preaches.
"Even if my kids had wanted to specialize in soccer, I wouldn't have let them," he says. "They all played multiple sports throughout high school and they have told me how glad they are that they did."
FEEDBACK
Wish we would have encouraged our son to lay off the soccer. He played
it year round for years and loved it very much. Now at 16 he will be
having surgery on both hips from overuse in his growth years!
Hopefully, he will come back from his operations ready to enjoy moving
with out pain.
-Delinda Irvine
http://www.athleticmanagement.com/2008/10/they_got_next.html
Thursday, November 27, 2008
Is regular exercise a friend or foe of the aging immune system? A systematic review
Science is slowly uncovering the connection between the immune system and exercise. Below is a great review of the recent science in this area. The short version is that some exercise is a small insult to the body, but the body builds up a resistance to it and is better than before!
Too much of an insult or too much exercise may not be good. No surprise there as anything that can help you, can also hurt you. Heck, you can even die from drinking too much water!
Be sure to check out this post from Dr. Lonnie Lowery HERE on inflammation, as it plays a very key role.
Time to grab that Kettlebell and get to work pumping up your immune system!
Newsletter Updates!
I am finally getting my newsletter up and going once again! More big things coming with it in 2009 and the release of the much anticipated MMA book and DVD set that I helped with science portion. You can sign up on the 3rd box on the upper right of my blog. I am working on a free report that should be completed around mid to late Jan 2009. Anyone who signs up now will receive it once it comes out for sure. I hate spam and promise I will NEVER sell your email address.
You can also recieve this blog directly into your mail box by signing up on the one just a bit below the newsletter link too.
Is regular exercise a friend or foe of the aging immune system? A systematic review.
Haaland DA, Sabljic TF, Baribeau DA, Mukovozov IM, Hart LE.
Clin J Sport Med. 2008 Nov;18(6):539-48
Rheumatology Division, Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada. haaland@mcmaster.ca
OBJECTIVE: The purpose of the current review is to synthesize the available evidence from prospective clinical trials that are relevant to the clinical question: "What, if any, are the effects of regular aerobic and/or resistance exercise on the immune system in healthy older adults?"
DATA SOURCES: Electronic databases were searched, using terms pertaining to immunology, exercise, and aging. Using the Ovid interface, the following databases were explored: Allied and Complimentary Medicine (AMED) (1985 to 2008), Cumulative Index to Nursing and Allied Health Literature (CINAHL) (1982 to 2008), all EBM Reviews (Cochrane DSR, ACP Journal Club, DARE, CCTR, CMR, HTA, and NHSEED), EMBASE (1980 to 2008), and MEDLINE (1950 to 2008). The MEDLINE database was searched a second time through the PubMed interface. STUDY SELECTION: Prospective controlled clinical trials were selected for review if they investigated the effects of an exercise intervention (minimum 4 weeks in duration) on an immune outcome measure in an older but otherwise healthy population. A total of 19 articles representing 17 trials were identified.
DATA EXTRACTION: Quality assessment of the relevant articles was performed using the Jadad et al criteria. Data extraction was performed using a standardized instrument. Data regarding the participants, interventions, and laboratory and clinical immunologic outcomes were synthesized.
DATA SYNTHESIS: Available data provide no clear evidence of acute or chronic effects of exercise on lymphocyte or natural killer (NK) cell numbers or phenotype (ie, surface markers)/activity, with 2 exceptions: (1) strength or endurance exercise may cause an acute transient elevation in circulating CD8+ T cells, and (2) regular aerobic exercise appears to enhance immunologic memory in the context of vaccination. The effects of strength training on NK cell activity are unclear. Furthermore, regular aerobic exercise appears to be associated with a reduction in chronic inflammation. Finally, no prospective controlled trials have clearly documented clinical immunologic benefits of regular exercise, which may well relate to underpowering of these studies.
CONCLUSIONS: Overall, in healthy older adults, regular, particularly aerobic, exercise appears to be a friend of the immune system, helping to offset diminished adaptive responses and chronic inflammation. The possibility exists that particularly strenuous exercise may cause acute immunologic changes, such as diminished NK cell activity, which could predispose to infection in certain individuals. However, given the possible benefits of regular exercise on the immune system and the many definite benefits on other systems, the evidence presented here should not dissuade practitioners from suggesting regular exercise to otherwise healthy older adults.
Wednesday, November 26, 2008
Testimonal: I Can Squat!!
Special thanks to Teresa for writing this up and taking a leap of faith to stop by for a Z Health session. Remember, your body is smart and wants to be healthy and move well; it just need a proper stimulus in order to get there many times.
Now, it is not always this easy; but from the stats I've been keeping, about 50-70% of the time it really is this easy with the correct exercises!
Testimonial
I can squat! Whoooo hooo!!
I started weight training in my early 40s and have been fairly successful at it. But one thing that always frustrated me was I could never squat properly. No matter what I tried, I could never get to parallel, unless my heels were significantly raised. I had pretty much resigned myself to being not built for squatting…or that it would take an enormous amount of detective and corrective work to remedy whatever was wrong structurally with me.
During my first session with Mike, I mentioned this almost as an aside. I showed him how tough it was for me to get even close to parallel with bodyweight. He told me I had weak hamstrings, among other things, and prescribed 4 very simple exercises to do three times a day. I’d read some of the testimonials from others, but I figured they were extreme examples. I hoped I’d see some improvements but wasn’t expecting anything dramatic.
Well during just my SECOND day of practice, I decided to try to squat with bodyweight. This is something I’ve come to do every now and then, just to see if anything had changed. Of course, over the years, nothing had and I would struggle to get even close to parallel. Well this particular morning, my second day of Z Health work, I tried a bodyweight squat in my kitchen. Strangely, I seemed to be going pretty deep. I had errands to run so I didn’t continue. When I got back home, I did my second round of exercises for the day, then decided to try some weighted squats. I took my 12kg kettlebell and tried a couple sets of goblet squats and a couple sets of one-arm front squats. Hmmm…it felt like I was going down further than I normally do. I checked in a mirror to make sure. Sure enough, I was hitting at least parallel on virtually each rep. There were even a few reps where I broke parallel!
This is unbelievable. I thought to make this much progress it would take endless trial and error, ferreting out errant body parts, working over and over. But this happened on just my second day! Unbelievable! I can squat!
--Teresa, Business Owner
Mike's notes
So what are you waiting for? Drop me a line and sign up for your Z Health session. For more information, see this link HERE.
Contact Mike T. Nelson to set up an appointment today (double click on my name for my email).
Jodie and I are off to South Padre Island, TX for a few days to get in some kiteboarding, socialize (wow, I get to see lots of friends all at once!) and get some reading in if the wind is low. My book list is piling up! I will be doing some work/research stuff too if the wind is low (bring on the wind!). I apologize if it takes me a few days to return your emails, but I will get back to you once I return if not sooner.
Happy Turkey everyone in the USA and happy weekend to those not in the USA.
Tuesday, November 25, 2008
Performance Research for November: Beta Alanine and Exercise Peformance
Be sure to see all the other blog posts I've done on beta alanine HERE.
There is also a review study at the bottom about the growing area of "functional foods"
Thoughts?
Mike N
The effects of beta-alanine supplementation and high-intensity interval training on neuromuscular fatigue and muscle function.
Smith AE, Moon JR, Kendall KL, Graef JL, Lockwood CM, Walter AA, Beck TW, Cramer JT, Stout JR.
Metabolic and Body Composition Laboratory, Department of Health and Exercise Science, University of Oklahoma, 1401 Asp Ave HHC 104, Norman, OK, 73019, USA. The purpose of this study was to determine the effects of beta-alanine supplementation and high-intensity interval training (HIIT) on electromyographic fatigue threshold (EMG(FT)) and efficiency of electrical activity (EEA). A total of 46 men completed four, 2-min work bouts on a cycle ergometer.
Using bipolar surface electrodes, the EMG amplitude was averaged and plotted over the 2-min. The resulting slopes were used to calculate EMG(FT) and EEA. Following initial testing, all participants were randomly assigned to either placebo (PL; n = 18), beta-alanine (BA; n = 18) or control groups (CON; n = 10). Following randomization, participants engaged in 6 weeks of HIIT training. Significant improvements in EMG(FT) and EEA resulted for both training groups.
Conclusion: In conclusion, high-intensity interval training appeared to be the primary stimulus effecting electromyographic fatigue threshold or efficiency of electrical activity, suggesting adaptations from high-intensity interval training may be more influential than increasing skeletal muscle carnosine levels on delaying fatigue in recreationally active men.
The effect of beta-alanine supplementation on neuromuscular fatigue in elderly (55-92 Years): a double-blind randomized study.
Stout JR, Graves BS, Smith AE, Hartman MJ, Cramer JT, Beck TW, Harris RC. Department of Health and Exercise Science,
University of Oklahoma, Norman, OK, USA. jrstout@ou.edu. ABSTRACT: BACKGROUND: Ageing is associated with a significant reduction in skeletal muscle carnosine which has been linked with a reduction in the buffering capacity of muscle and in theory, may increase the rate of fatigue during exercise. Supplementing beta-alanine has been shown to significantly increase skeletal muscle carnosine. The purpose of this study, therefore, was to examine the effects of ninety days of beta-alanine supplementation on the physical working capacity at the fatigue threshold (PWCFT) in elderly men and women.
METHODS: Using a double-blind placebo controlled design, twenty-six men (n = 9) and women (n = 17) (age +/- SD = 72.8 +/- 11.1 yrs) were randomly assigned to either beta-alanine (BA: 800 mg x 3 per day; n = 12; CarnoSyntrade mark) or Placebo (PL; n = 14) group. Before (pre) and after (post) the supplementation period, participants performed a discontinuous cycle ergometry test to determine the PWCFT.
RESULTS: Significant increases in PWCFT (28.6%) from pre- to post-supplementation were found for the BA treatment group (p < style="font-weight: bold;">
CONCLUSION: We suggest that BA supplementation, by improving intracellular pH control, improves muscle endurance in the elderly. This, we believe, could have importance in the prevention of falls, and the maintenance of health and independent living in elderly men and women.
Functional food for exercise performance: fact or foe?
Deldicque L, Francaux M.
Université catholique de Louvain, Institut d'éducation physique et de réadaptation, Louvain-la-Neuve, Belgium. PURPOSE OF REVIEW: To present food components showing evidence for improved sport performance in the light of the scientific literature from the past 2 years. RECENT FINDINGS: Appropriate nutrition is essential for sport performance. Nutritional products containing carbohydrates, proteins, vitamins, and minerals have been widely used by athletes to provide something extra to the daily allowance.
Currently, the field of interest is shifting from macronutrients and fluids to physiologically active isolated food components. Several of them have been demonstrated to improve sport performance at a higher level than expected with a well balanced diet. In the present review, we will focus on the benefits of creatine, caffeine, branched-chain amino acids, and more particularly leucine, beta-alanine, bicarbonate, and glycerol ingestion on exercise performance.
Conclusion: A bulk of products are sold on the market labeled with various performance benefit statements without any scientific evidence. These food components are often used without a full understanding or evaluation of the potential benefits and risks associated with their use. There is thus a real need to classify food components on the basis of their evidence-based effectiveness.
Any Thoughts on Accupunture and Pain?
Answer: Yes, there are some new data on the use of pain and acupuncture.
Note, for a review on my thoughts on pain, see the following posts
Myth Busters: Painful Soft Tissue Work
Pain Perception and the Neuromatrix of Pain
Pre-emptive Analgesics
Overload and Muscle Soreness (DOMS)
Recently there are 2 newer reviews on acupuncture and its effect upon pain.
The first one (below) is a review of 31 studies using acupuncture and sham acupuncture. Sham acupuncture is where they still poke you with a needle, but they are not putting it in the correct location. This is very important when reading studies (especially on acupuncture) since the placebo effect can be huge! Take one group and poke them with needles (acupuncture group) and don't do anything to the control group and many times you will see that the acupuncture group was better! Well, most in the treatment (acupuncture) group quickly figured out that they were in the treatment group and those that had nothing done quickly realized they were in the control group.
Many times it possible to have a control group. If you are doing a study on a new implantable medical device, it is considered unethical to implant the device in a group of patients that have NO medical need for it just to lessen the placebo effect. This can also make enrollment in some trials more difficult if the patients already believe the device will help them and may drop out if they are randomized to the control arm (no device).
So in our first acupuncture study they used only studies that had a comparison to the sham acupuncture group. They concluded "Needling acupuncture is superior to sham acupuncture and medication therapy in improving headache intensity, frequency, and response rate."
In the second study, they looked at post operative pain. While it does appear that they only took studies using acupuncture and a sham control procedure, it appears that there may be some benefit to acupuncture post surgery. Now this may be a placebo (not sure what they used for a sham control), but if by inserting a small needle into you allows your body to need fewer drugs for the same effect on pain--sign me up!
How does this relate to training?
1) Be sure to read studies closely and think about the placebo effect.
2) The mind is very powerful. You will achieve what you believe
Thoughts?
Acupuncture for the Management of Chronic Headache: A Systematic Review. Sun Y, Gan TJ. Duke University Medical Center, Department of Anesthesiology, Box 3094, Durham, NC 27710.
Anesth Analg. 2008 Dec;107(6):2038-2047.
OBJECTIVE: The objective of this review was to evaluate the efficacy of acupuncture for treatment of chronic headache.
METHODS: We searched the databases of Medline (1966-2007), CINAHL, The Cochrane Central Register of Controlled Trials (2006), and Scopus for randomized controlled trials investigating the use of acupuncture for chronic headache. Studies were included in which adults with chronic headache, including migraine, tension-type headache or both, were randomized to receive needling acupuncture treatment or control consisting of sham acupuncture, medication therapy, and other nonpharmacological treatments. We extracted the data on headache intensity, headache frequency, and response rate assessed at early and late follow-up periods.
RESULTS: Thirty-one studies were included in this review. The majority of included trials comparing true acupuncture and sham acupuncture showed a trend in favor of acupuncture. The combined response rate in the acupuncture group was significantly higher compared with sham acupuncture either at the early follow-up period (risk ratio [RR]: 1.19, 95% confidence interval [CI]: 1.08, 1.30) or late follow-up period (RR: 1.22, 95% CI: 1.04, 1.43). Combined data also showed acupuncture was superior to medication therapy for headache intensity (weighted mean difference: -8.54 mm, 95% CI: -15.52, -1.57), headache frequency (standard mean difference: -0.70, 95% CI: -1.38, -0.02), physical function (weighted mean difference: 4.16, 95% CI: 1.33, 6.98), and response rate (RR: 1.49, 95% CI: 1.02, 2.17).
CONCLUSION: Needling acupuncture is superior to sham acupuncture and medication therapy in improving headache intensity, frequency, and response rate.
Acupuncture and related techniques for postoperative pain: a systematic review of randomized controlled trials.
Sun Y, Gan TJ, Dubose JW, Habib AS.
Department of Anesthesiology, Duke University Medical Center, Box 3094, Durham, NC 27710, USA.
Br J Anaesth. 2008 Aug;101(2):151-60. Epub 2008 Jun 2.
Postoperative pain management remains a significant challenge for all healthcare providers. The objective of this systematic review was to quantitatively evaluate the efficacy of acupuncture and related techniques as adjunct analgesics for acute postoperative pain management. We searched the databases of Medline (1966-2007), CINAHL, The Cochrane Central Register of Controlled Trials (2006), and Scopus for randomized controlled trials (RCTs) using acupuncture for postoperative pain management. We extracted data about postoperative opioid consumption, postoperative pain intensity, and opioid-related side-effects. Combined data were analysed using a random effects model.
Fifteen RCTs comparing acupuncture with sham control in the management of acute postoperative pain were included. Weighted mean difference for cumulative opioid analgesic consumption was -3.14 mg (95% confidence interval, CI: -5.15, -1.14), -8.33 mg (95% CI: -11.06, -5.61), and -9.14 mg (95% CI: -16.07, -2.22) at 8, 24, and 72 h, respectively. Postoperative pain intensity (visual analogue scale, 0-100 mm) was also significantly decreased in the acupuncture group at 8 and 72 h compared with the control group.
The acupuncture treatment group was associated with a lower incidence of opioid-related side-effects such as nausea (relative risk, RR: 0.67; 95% CI: 0.53, 0.86), dizziness (RR: 0.65; 95% CI: 0.52, 0.81), sedation (RR: 0.78; 95% CI: 0.61, 0.99), pruritus (RR: 0.75; 95% CI: 0.59, 0.96), and urinary retention (RR: 0.29; 95% CI: 0.12, 0.74).
Perioperative acupuncture may be a useful adjunct for acute postoperative pain management.
Saturday, November 22, 2008
Everyone Needs a Coach/ Z Health Work from Brad Nelson
New blog post below that I reposted here from Mike T Nelson Training blog. I have every session I've done back to about Feb of 2007 logged there. It started as just a way for me to log what I was doing in a searchable format. I am also in an informal study looking at the effects of the Earth Pulse unit and wanted a way to track my results.
The earth pulse unit puts out pulsed magnetic waves to facilitate sleep and recovery. So far it really seems to help my cardiorespiratory fitness (CRF) but not too much of a change on strength (although others have reported great strength changes). I also normally don't have any problem sleeping at night either (getting enough sleep is an issue at times though). The unit is currently having some buttons fixed on it, so it will be interesting to compare the times of use and no use to see what changes occur.
I will keep you all updated and check out their link above for more information or click HERE for a coupon code to get $50 off of a unit (full disclosure, I do not get paid any money for any purchase of an earth pulse unit).
Training Goals
My main goal for training is to IMPROVE my life overall and I place movement quality as the highest priority that I want to improve. If a lift makes my movement worse, I simple don't do it since it is not meeting my current goals. The current cylce I am doing has the following goals after movement quality
1) increase deadlift (max single)
2) increase bench press (max single)
3) maintain CRF (cardiorespiratory fitness)
So keep that in mind when viewing, as what I do is customized for myself and my current goals; so it may or may not be best for you and your goals. I am happy to answer any questions on it though and as you can see I do eat my own dog food in respect to movement training.
Z Health Session
Went to see Brad "No Relation" Nelson for some Z work on myself this past Thursday
Wanted him to check my scar. In short, I have a midline scar on my chest that is about a foot long from when I have open heart surgery to fix and ASD (atrial septal defect) when I was 4.5 years old.
For background, see this link . In no way am I am complaining about this in any form, since without the surgery then I would have probably only made it to age 20 at best, so I am EXTREMELY thankful.
I am also doing some visual work since I currently have major suppression of my right eye. In essence, it would be the same for someone to do everything with only 1 eye (I don't have binocular vision currently), but I will get it figured out. I had a "lazy eye" when I was a kid and they patched my good eye so that my eyes would track normally.
Visual work background HERE.
Thursday's Work
So I wanted Brad to do some Z Health level 4 work around my scar. He found some big restrictions and quite a few released around the left side of my rib cage. At the end, the lower part of the scar was pretty good. Feels like the left side is twisted around from front to back. Makes sense since I had scoliosis growing up too. Brad was amazed that my upper back (outside of some sticky thoracic spots) is basically normally now. Before my scaps were quite twisted and stuck up funny like a stegosaurus!
Did some Z Health Cranial/Cervical Spine work. Homework drills are
Posterior glide, hold and lateral tilt to the right
Posterior glide, hold, move jaw right, hold, then lateral tilt to the right
Left feeling great! Thoracic felt awesome! Did some Brock string work and not a huge change, by my right eye stays on now for a few seconds and flashes off and on withOUT hold my scar or having it taped. Still a ways to go, but overall movment felt great. Had more energy, did a DL session in the afternoon that felt better than it has prett much ever (with a straight bar) and bench session that night went great. Had training partner check my thoracic spine at the end and it was the best he has ever seen so far. Felt great, had more energy although my face became quite flush/red during the day and after doing the exercises, but went away by the next day.
Why Am I Telling You This?
The whole point is that EVERYONE NEEDS A COACH! While it is true that I should know my body better than anyone else, I can't watch my movement all the time.
Having feedback about your movement and asking for help is NOT a sign of weakness, but a sign of strength. There are many that are willing to help you reach your goals, so reach out to them NOW! It is NEVER the right time, so if it is important to take the first step TODAY.
Thanks again to Brad "No Relation" Nelson again. Be sure to check out his services and Kettlebell Classes here at Kinetic Edge Performance. I am extremely picky about who I work with and who I allow to do work on myself, and I highly recommend Brad.
Rock on
Mike N
Wednesday, November 19, 2008
Women and Weights--But I Don't Want to Get Too Big!
The reality is that most guys need to check their ego and cut back on the weight and focus on fixing their skitzoid form. Most women need to lift heavier.
When a woman athlete asks me how heavy the kettlebell she is working with, my standard answer is 16. They carry on knocking out KB swings no problem. Most are then shocked that it was actually 16 KILOGRAMS (about 35 pounds) since they did not believe they could lift that much. I tried telling a few how much it was in pounds before they started in the past and I had one that refused to try it since she was already convinced that they could not do it. Remember, the body does what the mind believes.
Muscle is more DENSE than fat, so it takes up less space for the same amount of weight. It also is a primary regulator of your metabolic rate; so more muscle = more caloires burned while NOT exercising. I have yet to meet one female athlete that wants to live the rest of her life only eating 1,000 calories a day. More muscle = the more you can eat and still fit in your skinny jeans.
Below is a video of some local female powerlifters. Heck, they are lifting more than some guys in the gym and none of them are remotely close to being too big; so relax and go lift some heavy stuff.
Congrats to Maura, Fawn, Cheryl, and Anna! Awesome work!!
If you are guy and are interested in getting your hyooooogeness on, check out an older blog post I did on "I wanna get hyoooooge" HERE
Tuesday, November 18, 2008
Rebuttal to Recent Attacks Against Dietary Supplements
Greetings to all my loyal readers. My study looking at the possible effect of Energy Drinks is fully approved now! Whoo ha! More info to come soon.
Antioxidants
So antioxidants are in the news again and I was going to write up a review of some of the recent literature, but the kind folks at Life Extension Foundation had already done one up that was just plain awesome--so here it is below.
I am working on more great info soon and my research is causing some less frequent updates here, but I will work on getting it to you as soon as I can.
Rock on!
Mike N
From Life Extension Foundation
Preliminary Rebuttal to Recent Attacks Against Dietary Supplements
By William Faloon
The media recently ran headline news stories claiming that vitamins C, D and E do not prevent heart attack, stroke or breast cancer. This report represents Life Extension’s preliminary response to these media attacks that are based on egregiously flawed studies. We will submit this report for formal peer review and referencing and expect to post our official report within a few weeks.
Needless to say, when these biased attacks are launched, we are not given prior notice so that our side of the story makes it into the mass media.
In the early 1990s, several large population studies showed significant reductions in cardiovascular disease in those who consumed vitamin C or vitamin E.
The most widely reported study emanated from UCLA, where it was announced that men who took 800 mg a day of vitamin C lived six years longer than those who consumed the recommended daily allowance of 60 mg a day. The study, which evaluated 11,348 participants over a 10-year period of time, showed that higher vitamin C intake reduced cardiovascular disease mortality by 42%.
These kinds of findings did not go unnoticed by the federal government, who subsequently invested hundreds of millions of dollars in an attempt to ascertain if relatively modest vitamin doses could prevent common age-related diseases.
In a study that received extensive media coverage, four groups of male doctors were given various combinations of vitamin C and/or vitamin E or placebo. After eight years, there was no reported difference in heart attack or stroke incidence among the groups. This led the media to state that consumers should not buy these supplements.
As you will read, there were so many egregious flaws in this study that the findings are rendered meaningless. Regrettably, consumers who trust their lives to the mainstream media may fall victim to this latest charade to discredit validated methods to reduce cardiovascular disease risk.
Do you take your vitamins every other day?
The study subjects in the vitamin E groups were told to take one 400 IU capsule of synthetic alpha tocopherol every other day. This design flaw raises several issues that are rather obvious to serious supplement takers.
First of all, we don’t take our vitamins every other day. Free radicals are constantly being generated in our bodies, and supplement users today seek to take their antioxidants with most meals, as oxidative damage is generally the greatest after eating.
It is rather ludicrous to think that these study subjects would reduce their vascular disease risk by taking modest dose, every other day, of a form of vitamin E with inferior anti-oxidant capacity.
If one were to rely only on synthetic alpha tocopherol, the minimum daily dose needed has been shown to exceed 800 IU, far greater than the 400 IU ingested every other day by the subjects in this poorly designed study.
Serious supplement users normally take 400 IU every day of natural vitamin E along with a plethora of complimentary nutrients. We would not expect 400 IU of synthetic vitamin E taken every other day to produce much of an effect. Yet that is the dose given to these study subjects with the expectation that this would show a reduction in cardiovascular disease. This is by no means the only flaw of this study.
Natural versus synthetic vitamin E
There was a long standing debate as to whether natural or synthetic vitamin E is better. For most vitamins, there is no difference between natural and synthetic. In fact, for most vitamins, the only forms available are synthetic. With vitamin E, however, the natural form has proven far superior.
Natural vitamin E is distributed through the body much better than the synthetic form. The reason is that specific carrier proteins in the liver selectively bind to natural vitamin E and transport it through the blood to cells throughout the body. These carrier proteins only recognize a portion of synthetic vitamin E and ignore the remainder.
Japanese researchers gave natural or synthetic vitamin E to young women to measure how much vitamin E actually made it into their blood. It took only 100 mg (149 IU) of natural vitamin E to produce blood levels that required 300 mg (448 IU) of synthetic vitamin E.
Most studies show that synthetic vitamin E is only half as active in the body as the natural form. As it relates to the flawed study claiming that vitamin E does not prevent heart attack, the 400 IU of synthetic alpha tocopherol given every other day equates to only 100 IU a day of the natural form.
We would not expect 100 IU of natural vitamin E a day by itself to necessary reduce vascular disease risk. As you continue to read, however, there are many other flaws in this study that render its conclusions useless.
Note: When checking vitamin labels, natural vitamin E is usually stated as the “d” form (for example d-alpha tocopheryl acetate,d-alpha tocopherol, and d-alpha tocopheryl succinate). Synthetic vitamin E will have a “l” after the “d” (for example, dl-alpha tocopheryl acetate, dl-alpha tocopheryl succinate, dl-alpha tocopherol). Remember – “dl” signifies synthetic vitamin E, whereas “d” signifies natural vitamin E. Remember that if you are getting 400 IU of natural d-alpha tocopherol (d-alpha tocopheryl succinate or acetate) it is equal to about 800 IU of synthetic dl-tocopherol (dl-alpha tocopheryl acetate or succinate).
Vitamin C potencies too low
If all you are going to take to protect against free radical damage is vitamin E and/or vitamin C, then you will need far greater potencies than were given to the study subjects in this flawed study.
Published studies that document vascular benefits in response to vitamin C typically use doses of 1,000-6,000 mg each day. The authors of the flawed study alluded to this when they stated:
“In a pooled analysis of 9 cohorts, vitamin C supplement use exceeding 700 mg/day was significantly associated with a 25% reduction in coronary heart disease risk.”
Since the doctors who designed the flawed study knew that vitamin C intakes exceeding 700 mg a day significantly reduce heart attack rates, we can not figure out why they limited their subject’s daily dose to only 500 mg.
Two-time Nobel Prize laureate Linus Pauling and his associates advocated daily doses of vitamin C ranging from 10,000 to 20,000 mg to protect against heart attack. Linus Pauling’s theory was that atherosclerosis is primarily caused by insufficient vitamin C intake. Dr. Pauling compared the high amount of vitamin C naturally synthesized in the bodies of animals that don’t typically die of heart attacks. A 150 pound goat, for example will maintain an ascorbate blood concentration equivalent to ingesting 13,000 mg of vitamin C.
Unlike most animals, humans lack an internal enzyme needed to manufacture vitamin C in their body. If humans don’t obtain enough vitamin C from external sources, they die acutely from scurvy, or according to Linus Pauling…slowly suffer atherosclerotic occlusion. Dr. Pauling crusaded to educate humans about the need to take mega-doses of vitamin C.
Dr. Pauling and his associates published papers stating that when vitamin C levels are insufficient, the body uses cholesterol to repair the inner lining of arteries. Dr. Pauling believed that cholesterol’s involvement in atherosclerosis was a direct result of insufficient vitamin C.
Life Extension has long recommended that its members take at least 2,000 mg a day of vitamin C, along with potent plant extracts to enhance the biological benefits of ascorbate inside the body. The 500 mg daily dose of vitamin C given to the subjects of this flawed study was clearly inadequate. This did not stop the headline-hungry media and many conventional doctors from recommending that aging humans avoid these supplements altogether.
As we noted already, the dose of vitamin E used in this study was also too low to expect a reduction in vascular disease events. While alpha tocopherol vitamin E is a classic antioxidant, its free radical quenching efficacy pales in comparison to polyphenol extracts from green tea, pomegranate, grape-seed and blueberry.
Based on the superior antioxidant properties of plant extracts such as pomegranate, health conscious people today are able to obtain greater protection against free radicals and enhance the efficacy of the vitamin C without necessarily having to take the mega-doses recommended by Linus Pauling. On the flip-side, to attack the value of vitamin C based on a group of doctors who took only 500 mg a day does not correspond to the doses scientific studies show are needed to prevent heart attack.
Alpha tocopherol displaces gamma tocopherol
An increasing number of scientists are questioning the wisdom of administering alpha tocopherol vitamin E by itself. The reason is that alpha tocopherol displaces critically important gamma tocopherol in the body. The authors of the flawed study admitted that the failure to include gamma tocopherol may have been a reason that no effect was seen in the alpha tocopherol groups. Here is a quote directly from the flawed study:
"Moreover, PHS II and other prevention trials have used alpha-tocopherol, whereas the gamma-tocopherol isomer also may have a role in cardiovascular disease prevention because it has greater efficacy than alpha-tocopherol to inhibit lipid peroxidation and it may be suppressed in the presence of alpha-tocopherol."
The above admission understates the critical importance that gamma tocopherol plays in maintaining arterial health. While alpha tocopherol helps protect against lipid peroxidation, gamma tocopherol is required to neutralize the dangerous peroxynitrite free radical. Peroxnitrite damages arteries because:
- Peroxnitrite promotes the oxidation of alpha tocopherol, thereby depleting the body of the vitamin E needed to protect against oxidation of the lipid moiety (part) of LDL. LDL is composed of both lipid and protein parts (moieties), and oxidation associated with both moieties has been implicated in atherosclerosis. In a fascinating paradox, when alpha tocopherol is given without gamma tocopherol, the result is that alpha tocopherol itself can be neutralized in the body by the peroxynitrite free radical. This in turn promotes oxidation of the lipid moiety of LDL , a major step on the path towards atherosclerosis.
- Peroxnitrite promotes LDL protein oxidation. While alpha tocopherol inhibits LDL lipid peroxidation, gamma tocopherol is needed to protect against oxidation of the protein moiety (part) of LDL.
In the absence of gamma tocopherol, which can occur when alpha tocopherol is given without gamma tocopherol, both LDL lipid and protein oxidation is increased, which reveals the egregious mistake of trying to prevent vascular disease by administering only alpha tocopherol. Health conscious individuals should be assured that other nutrients such a lipoic acid and polyphenol plant extracts also block protein and lipid LDL oxidation.
Some studies suggest that only gamma tocopherol prevents heart attacks. As it relates to atherosclerosis, gamma tocopherol blood concentrations have been reported to be significantly lower in coronary heart disease patients than in healthy control subjects. While alpha and gamma tocopherols each perform life-sustaining functions, only gamma tocopherol increases endothelial nitric oxide protein expression. As I will describe next, a deficit of nitric oxide in the endothelium is a primary cause of arterial disease.
Primer on Alpha and Gamma Tocopherol
Alpha tocopherol and gamma tocopherol are the two major forms of vitamin E in human plasma. The dietary intake of gamma tocopherol is generally two- to four-fold higher than that of alpha tocopherol. Alpha tocopherol plasma levels, however, are about four-fold higher than those of gamma tocopherol. One reason is that there is a preferential cellular uptake of gamma tocopherol over alpha tocopherol.
Scientific studies consistently show that gamma tocopherol plays a significant role in modulating intracellular antioxidant defense mechanisms. Interestingly, the presence of gamma tocopherol dramatically increases the cellular accumulation of alpha tocopherol.
A hidden cause of heart attack and stroke
Even when all conventional risk factors are controlled for, the progressive decline of nitric oxide involving the arterial wall (the endothelium) too often leads to coronary heart attack and stroke.
Seven years ago, Life Extension researchers identified a critical compound (tetrahydrobiopterin) that is essential for the synthesis of nitric oxide in the endothelium. We spent several hundred thousand dollars trying to develop an affordable way to manufacture this compound as it offered tremendous promise for eradicating atherosclerosis.
We failed to find an affordable way to make tetrahydrobiopterin. The good news is that nutrients that suppress peroxynitrite (like gamma tocopherol and pomegranate) increase endothelial nitric oxide by blocking the oxidation of tetrahydrobiopterin.
Indeed, clinical studies show that supplemental gamma tocopherol enhances platelet endothelial nitric oxide synthase activity. Furthermore, a diet high in gamma tocopherol rich walnuts improved endothelium-dependent vasodilation in those with high cholesterol.
By administering only alpha tocopherol as was done in the flawed study, one would expect gamma tocopherol to be suppressed, peroxynitrite levels to increase, and precious tetrahydrobiopterin to be oxidized, thus depriving the endothelium of the nitric oxide it needs to protect against heart attack and stroke. Is it any wonder that this study failed to show vascular disease reduction in those given only alpha (but not gamma) tocopherol?
Failing to account for all vascular risk factors
Numerous independent risk factors are associated with the development of atherosclerosis and subsequent heart attack and stroke risk. A major flaw in this study was expecting low-dose vitamin C and/or E to somehow overcome all of these underlying causes of artery disease.
We know it is impossible for vitamins C and E to overcome these many risk factors, but this did not stop the media from recommending that Americans discard their supplements.
The following represents a succinct list of documented vascular disease risk factors:
- Low testosterone (in men)
- Excess fibrinogen
- Low HDL
- Excess LDL and total cholesterol
- Excess glucose
- Excess C-reactive protein
- Excess homocysteine
- Hypertension
- Low EPA/DHA
- Low vitamin D
- Excess insulin
- Excess estrogen (in men)
- Oxidized LDL
- Excess platelet activity
- Nitric oxide deficit (endothelial dysfunction)
The basis for doing this study, as outlined by the study’s authors, was to use vitamins C and/or E to:
- Trap organic free radicals
- Deactivate excited oxygen molecules
- Prevent tissue damage
- Inhibit LDL oxidation
- Modify platelet activity
- Reduce thrombotic potential
- Modify vascular reactivity
As one can clearly see, there are 15 documented cardiovascular risk factors. Yet only 3 of these risk factors are what formed the basis for conducting this clinical trial using low-dose vitamin C and/or E. The 3 known risk factors the authors of the flawed study expected to favorably influence with vitamins C and E were:
- LDL oxidation
- Platelet activity and thrombotic potential
- Vascular reactivity (another term for endothelial dysfunction)
For every one mechanism the study’s authors proposed might enable low-dose vitamin C and/or E to work, there were five additional risk factors that would not be corrected. For instance, vitamins C and E in these low doses are not going to reduce C-reactive protein, homocysteine, fibrinogen, or glucose. Vitamins C and E in any dose are not going to increase testosterone, decrease estrogen, or provide cardio-protective EPA/DHA and vitamin D.
On the contrary, as we have already shown, by giving only alpha but not gamma tocopherol, one might expect increased LDL oxidation and impaired endothelial function. That’s because alpha tocopherol displaces gamma tocopherol in the body. Gamma-tocopherol suppresses the peroxynitrite radical that oxidizes both LDL protein and the tetrahydrobiopterin that is needed to produce endothelial nitric oxide.
As far as platelet activity and thrombotic potential (abnormal clotting inside a blood vessel) are concerned, gamma tocopherol is significantly more potent than alpha tocopherol in inhibiting platelet aggregation that can lead to a heart attack or stroke. By displacing gamma tocopherol, the alpha tocopherol used alone in this study may have increased abnormal platelet aggregation risk.
From everything we know today, this study was designed to fail. Not only did it not correct for the major causes of vascular disease, but it may have exacerbated some of the more dangerous ones.
None of what I wrote so far may really matter
You have just learned why low-dose vitamin C and/or E supplementation would not be expected to reduce heart attack and stroke risk.
I have saved the biggest shocker for last. It turns out that a significant number of the study subjects (who were all medical doctors) who were supposed to take the vitamin C and/or E supplements did not take their pills. Yet when the calculations for heart attack or stroke incidence were made, those who took as little as 66% of their low-dose vitamin C and/or E supplements were counted as having taken the entire dose.
At the end of the study, 28% of the study subjects admitted they had not even taken 66% of their low-dose vitamin C and/or E supplements.
Even more troubling is the method used to track who was really taking their supplements. Participants were asked to remember and track supplement usage for over 8 years’ time without any verification of actual pill counts, compliance by plasma antioxidant analysis, or in vivo surrogate markers of oxidant stress. Relying upon participants’ memory & recollection over a lengthy time period of many years is a rather pathetic way of ensuring adherence, and renders the author’s so called “sensitivity analysis” meaningless.
The lack of adherence, i.e. the fact that a significant percentage of the study participants were not even taking their vitamins may be the most significant flaw to this study. No one in the mainstream media bothered to report this, or any of the other flaws that jumped out at us.
Instead, the media’s message was don’t waste your money on vitamin C or E pills. Many supplement users who are taking the right form and dose of their vitamin C and E nutrients may believe the media’s biased reporting. Even those who take low-dose vitamin supplements may discontinue, which as you will read next is regrettable from a public health standpoint (but great news for the pharmaceutical companies).
Shocking deficiencies of vitamin E
The media used this horrifically flawed study as a basis to steer Americans away from vitamin C and E supplements. It’s as if all of the previous positive published studies disappeared overnight.
What was omitted is the fact that 93% of American men and 96% of American women do not consume the recommended dietary allowance of vitamin E in their diet. The federal government says Americans need only 15 milligrams a day of vitamin E, yet even this minute amount is not found in the diets of the vast majority of people.
This means that most Americans require a vitamin E supplement to avoid a chronic deficiency, but this important fact was conveniently left out of the news stories.
Conventional medicine says that severe vitamin E deficiency results mainly in neurological symptoms such as impaired balance and coordination and muscle weakness. These neurological symptoms do not develop for 10-20 years; as it takes time for free radicals to inflict nerve damage in the absence of sufficient vitamin E. The reality is that chronic vitamin E deficiency adversely impacts virtually every cell of the body.
A media coup for pharmaceutical companies
The optimal moment of the year to get your message to the masses is the second week of November. This is a time in between holidays, when winter is setting in, and few people are on vacation. The television networks consider this their most important “sweeps week” as it provides the most accurate measurement of their ratings.
The timing of the release of this horrendously flawed vitamin C and E study could not have been more perfect for pharmaceutical interests. It came out less than one week after the November election when the media was primed to sensationalize any story that would attract viewers for their all important “sweeps week”.
On the very same day the media launched its attack on vitamins C and E, the same news sources reported that the statin drug Crestor® reduced heart attack rates by 44% in healthy people who had high C-reactive protein levels. Just think, as an uneducated consumer, you read on the same day that vitamins C and E are worthless and an expensive statin drug works miracles.
Financial analysts predict a windfall for the makers of Crestor® based on this widely distributed report. In retrospect, conducting this study only on people with high C-reactive protein (but not particularly high LDL) was a brilliant marketing strategy. It had a high probability of a successful outcome, and if the study failed, Crestror® was never approved to lower C-reactive protein or be used in this population group anyway, so the pharmaceutical company had nothing to lose.
We at Life Extension have long warned about the vascular dangers of elevated C-reactive protein and even recommended statin drugs if natural approaches fail to reduce C-reactive protein. We don’t believe most people have to purchase expensive brand name drugs like Crestor®, as generic simvistatin (name brand Zocor®) or pravastatin (name brand Pravachol®) can provide similar benefit at a fraction of the price.
Media also attacks vitamin D
Not content to bash only vitamins C and E, the media the very next day in November ran a headline story stating that “Supplements don’t reduce breast cancer risk”. This story was based on a study of women who received only 400 IU a day of supplemental vitamin D.
As has been reported for years in this and other health publications, 400 IU a day of vitamin D is clearly inadequate. To reduce breast cancer risk by around 50%, a daily dose of 1000 IU and higher is required. The major flaw in this study is that participants in the active and placebo group were allowed to take vitamin D outside the study, which rendered the findings meaningless even if the proper dose has been given.
The fact that the media made this study headline news is regrettable because only about 20% of the study population achieved a 25-hydroxy vitamin D at the minimum dose required to prevent breast cancer (greater than 30 ng/mL). In other words, most participants in the active or placebo group failed to achieve even the minimal blood concentrations of vitamin D that other studies document are needed to protect against breast cancer. So all this study did was help confirm what vitamin D experts have been saying for over five years now, i.e. a minimum of 800 IU to 1000 IU of vitamin D a day is required.
Don’t be a victim of this flawed propaganda
It is in the economic interests of drug companies to steer Americans away from healthier lifestyles and dietary supplements. As more Americans fall ill to degenerative disease, drug company profits increase exponentially.
Enormous amounts of pharmaceutical dollars are spent influencing Congress, the FDA, and other federal agencies. The result is the promulgation of policies that cause Americans to be deprived of effective, low-cost means of protecting themselves against age-related disease.
As a member of the Life Extension Foundation, you gain access to scientific information that is interpreted in the context of what health conscious people are really doing to protect themselves against common diseases. This information is too often distorted by the government, drug companies and the media.
For longer life,
William Faloon