Saturday, May 30, 2009
ACSM update and new hydrolyzed protein study
Greetings from Seattle WA. I just have a sec here due to limited internet access and more things to do yet today; but wanted to get this brand new study out to all of you.
Jodie and I just finished an amazing breakfast here by our kind hosts. Fresh espresso, pumpkin pancakes and an omelet with red pepper and roasted garlic. Yummmmmy.
ACSM was killer and tons of info coming soon (soon being early this coming week as I may not have Internet access until then). I cut down on my notes this year and only have 20 pages.
Dave Barr and I saw a killer lecture from Dr. Stu Phillips about testosterone levels and training--short version is that if you are in the normal range, being high or low will NOT accelerate or alter muscle size or strength gains (this excludes the very very low end and the very very high end--those using exogenous testosterone). Exclusive updates to my newsletter group too (thanks for your patience).
Here is the study
Am J Clin Nutr. 2009 May 27, 2009
Ingestion of a protein hydrolysate is accompanied by an accelerated in vivo digestion and absorption rate when compared with its intact protein.
Koopman R, Crombach N, Gijsen AP, Walrand S, Fauquant J, Kies AK, Lemosquet S, Saris WH, Boirie Y, van Loon LJ.
BACKGROUND: It has been suggested that a protein hydrolysate, as opposed to its intact protein, is more easily digested and absorbed from the gut, which results in greater plasma amino acid availability and a greater muscle protein synthetic response.
OBJECTIVE: We aimed to compare dietary protein digestion and absorption kinetics and the subsequent muscle protein synthetic response to the ingestion of a single bolus of protein hydrolysate compared with its intact protein in vivo in humans.
DESIGN: Ten elderly men (mean +/- SEM age: 64 +/- 1 y) were randomly assigned to a crossover experiment that involved 2 treatments in which the subjects consumed a 35-g bolus of specifically produced l-[1-(13)C]phenylal anine-labeled intact casein (CAS) or hydrolyzed casein (CASH). Blood and muscle-tissue samples were collected to assess the appearance rate of dietary protein-derived phenylalanine in the circulation and subsequent muscle protein fractional synthetic rate over a 6-h postprandial period.
RESULTS: The mean (+/-SEM) exogenous phenylalanine appearance rate was 27 +/- 6% higher after ingestion of CASH when compared with CAS (P < p =" 0.10)." style="font-weight: bold;">CONCLUSIONS: Ingestion of a protein hydrolysate, as opposed to its intact protein, accelerates protein digestion and absorption from the gut, augments postprandial amino acid availability, and tends to increase the incorporation rate of dietary amino acids into skeletal muscle protein.