Showing posts with label ACSM. Show all posts
Showing posts with label ACSM. Show all posts

Saturday, May 30, 2009

ACSM update and new hydrolyzed protein study


Greetings from Seattle WA. I just have a sec here due to limited internet access and more things to do yet today; but wanted to get this brand new study out to all of you.

Jodie and I just finished an amazing breakfast here by our kind hosts. Fresh espresso, pumpkin pancakes and an omelet with red pepper and roasted garlic. Yummmmmy.

ACSM was killer and tons of info coming soon (soon being early this coming week as I may not have Internet access until then). I cut down on my notes this year and only have 20 pages.

Dave Barr and I saw a killer lecture from Dr. Stu Phillips about testosterone levels and training--short version is that if you are in the normal range, being high or low will NOT accelerate or alter muscle size or strength gains (this excludes the very very low end and the very very high end--those using exogenous testosterone). Exclusive updates to my newsletter group too (thanks for your patience).

Here is the study

Am J Clin Nutr. 2009 May 27, 2009

Ingestion of a protein hydrolysate is accompanied by an accelerated in vivo digestion and absorption rate when compared with its intact protein.

Koopman R, Crombach N, Gijsen AP, Walrand S, Fauquant J, Kies AK, Lemosquet S, Saris WH, Boirie Y, van Loon LJ.

BACKGROUND: It has been suggested that a protein hydrolysate, as opposed to its intact protein, is more easily digested and absorbed from the gut, which results in greater plasma amino acid availability and a greater muscle protein synthetic response.

OBJECTIVE: We aimed to compare dietary protein digestion and absorption kinetics and the subsequent muscle protein synthetic response to the ingestion of a single bolus of protein hydrolysate compared with its intact protein in vivo in humans.

DESIGN: Ten elderly men (mean +/- SEM age: 64 +/- 1 y) were randomly assigned to a crossover experiment that involved 2 treatments in which the subjects consumed a 35-g bolus of specifically produced l-[1-(13)C]phenylal anine-labeled intact casein (CAS) or hydrolyzed casein (CASH). Blood and muscle-tissue samples were collected to assess the appearance rate of dietary protein-derived phenylalanine in the circulation and subsequent muscle protein fractional synthetic rate over a 6-h postprandial period.

RESULTS: The mean (+/-SEM) exogenous phenylalanine appearance rate was 27 +/- 6% higher after ingestion of CASH when compared with CAS (P < p =" 0.10)." style="font-weight: bold;">CONCLUSIONS: Ingestion of a protein hydrolysate, as opposed to its intact protein, accelerates protein digestion and absorption from the gut, augments postprandial amino acid availability, and tends to increase the incorporation rate of dietary amino acids into skeletal muscle protein.

Tuesday, May 26, 2009

Performance Research for May: Fat Loss and Exercise

Greetings from sunny Seattle WA. Yes, it is actually sunny out here!

Jodie and I finally made it here ok and we are off to tour the Space Needle, the Experience Music exhibit and Jim Hensen's Muppets exhibit too

I am off to ACSM tomorrow through Friday, so I will hopefully have updates here but that will all depend on my internet connection. I will have exclusive newsletter only updates for my newsletter friends too.

A few short studies on fat loss in the meantime.

Addition of aerobic exercise to a weight loss program increases BMD, with an associated reduction in inflammation in overweight postmenopausal women.

Silverman NE, Nicklas BJ, Ryan AS. University of Maryland School of Medicine, Geriatric Research, Education and Clinical Center of the Baltimore Veterans Affairs Medical Center, GRECC (BT/18/GR), 10 North Greene Street, Baltimore, MD 21201-1524, USA.


Increased inflammation and weight loss are associated with a reduction in bone mineral density (BMD). Aerobic exercise may minimize the loss of bone and weight loss may contribute to a decrease in cytokines. We tested the hypothesis that aerobic exercise in combination with a weight loss program would decrease circulating concentrations of inflammatory markers, thus mediating changes in BMD. This was a nonrandomized controlled trial. Eighty-six overweight and obese postmenopausal women (50-70 years of age; BMI, 25-40 kg/m(2)) participated in a weight loss (WL; n = 40) or weight loss plus walking (WL + AEX; n = 46) program. Outcome measures included BMD and bone mineral content of the femoral neck and lumbar spine measured by dual energy X-ray absorptiometry, interleukin-6, tumor necrosis factor-alpha, soluble receptors of IL-6, and TNF-alpha (sTNFR1 and sTNFR2; receptors in a subset of the population), VO(2) max, fat mass, and lean mass.


Weight decreased in the WL (p < p =" 0.001)," style="font-weight: bold;">


CONCLUSION: Our findings suggest that the addition of aerobic exercise is recommended to decrease inflammation and increase BMD during weight loss in overweight postmenopausal women.

My notes: Nothing earth shattering here---you need to EXERCISE (heck, even walking) for weight loss and better health (less inflammation).


Effect of calorie restriction on subjective ratings of appetite.

Anton SD, Han H, York E, Martin CK, Ravussin E, Williamson DA. Pennington Biomedical Research Center, Baton Rouge, LA, USA. santon@aging.ufl.edu


BACKGROUND: Energy or calorie restriction (CR) has consistently been shown to produce weight loss and have beneficial health effects in numerous species, including primates and humans. Most individuals, however, are unable to sustain weight losses induced through reductions in energy intake, potentially due to increased hunger levels. The effects that prolonged CR has on subjective aspects of appetite have not been well studied. Thus, the present study tested the effect of 6 months of caloric restriction on appetite in healthy, overweight men and women.

METHODS: Forty-eight overweight men and women with a body mass index (BMI; kg m(-2)) between 25-29.9 took part in a 6-month study and were randomised into one of four groups: healthy diet (control); 25% CR; 12.5% CR plus exercise (12.5% increased energy expenditure; CR + EX); low-calorie diet [LCD; 3724 kJ day(-1) (890 kcal day(-1)) until 15% of initial body weight was lost, then maintenance]. Appetite markers (i.e. hunger, fullness, desire to eat, etc.) were assessed weekly during a fasting state.


RESULTS: Body weight was significantly reduced in all three energy-restricted groups (CR = -10.4 +/- 0.9%; CR + EX = -10.0 +/- 0.8%; and LCD = -13.9 +/-0.7%), indicating that participants were adherent to their energy restriction regimen, whereas the healthy diet control group remained weight stable (control = -1.0 +/- 1.1%). Despite these significant weight losses, appetite ratings of participants in the three energy-restricted groups at month 6 were similar to the weight stable control group.


CONCLUSIONS: CR regimens with low fat diets producing significant weight losses have similar effects on appetite markers over a 6-month time period compared to a weight stable control group.

My notes: I wish they would have measured body fat instead of just using weight and BMI. You want to drop fat NOT muscle; but if you only measure weight you don't know if you are dropping muscle and fat.


Saturday, May 23, 2009

Cardiobots and Cardio Bunnies--Stick to the Hornet's Nest

I just have a sec as Jodie and I are off to the airport in a bit for Seattle WA for 8 days. Well, we were supposed to be on a plane now but there was a change to our flight time and the plane already left at 6:30am instead of 2:30pm today! Thanks for the great notice!
All the details will be in my newsletter that goes out tomorrow if anyone is interested (can still sign up at the bottom on this message).

Some good friends of mine were kind enough to open up their house to us (little do they know what is in store) and time for a much needed vacation. Neither of us have been to Seattle yet either and I will be a the American College of Sports Medicine (ACSM) conference this coming Wed-Fri sniffing out the latest and greatest for all of you here. I am working on some special updates and perhaps even an interview(s). Some of it will be released here and some tidbits will only be sent to my newsletter group, so be sure to sign up for my newsletter at the end of this post (it is free too).

If you are going to be at ACSM, drop me a note and we can chat live in person!

So it looks like a previous blog post I did stirred up a few comments and I got permission to post one below as this weeks "Letter to the Editor"

Read on

Ok, time for me to say something about the language you use as you may be hurting yourself and not even realize it. First, let me say, I love your blog posts, I can tell you spend a great deal of time and effort to not only "just post links to research articles", but you take the time and effort to break down the research articles and you do an excellent job of summarizing and breaking it down to a lay person's level, who, may be interested and intelligent enough to really "get" the article, but who may not be willing to dedicate the time to actually read the whole study, in part b/c you break it down so well!

Constructive Criticism Details below:
Anytime you write on your blog or in these email updates to your blog about strength training, you refer to it as "strength training" or as training for "power/speed athletes", but I have Never read you making Any derogatory remarks about strength training.

Except for the one blog post about "Broscience".
At the same time, I have observed, that almost anytime you write, on your blog, or in these email updates to your blog, about endurance training, you Almost Always refer to it as exercise conducted by "cardio bunnies" or as exercise conducted by (in this case) "Cardiobots", or you may use some other derogatory word, but "Cardio bunnies" seems to be your favorite.

And I get that there are people out there who "only" will do endurance training, and I can see how you may feel that strength training is not stressed enough or paid enough attention to and therefore I can see that you may be trying to make a case for why strength training is important. However, at the same time, I think there are probably just as many people out there who "only" engage in strength training and don't see any value in endurance training. And I know, you know the value in endurance training, b/c I've read a number of your blog posts about how amazing you find endurance athletes like the bike race across America.


Plus, I know you are very smart and as a smart person myself (at least I like to think so), who tries to have a good balance of both endurance and strength training, I find it demeaning and simply not necessary, to almost Always make fun of people who engage in endurance training by calling them demeaning names.


This all leads to my question:
Why do feel it is necessary to make derogatory remarks about endurance training or people who engage in endurance training, but you (almost) never make derogatory remarks about strength training or people who engage in it, but you in strength training?

Charles


Thanks again for the comments Charles. Much appreciated as it take cajones to actually give constructive feedback.

Yeah, I may be pissing off some cardio people although that is not my intent. I refer to a cardiobot or a cardio bunny as someone who does mindless hours of cardio normally on a treadmill or elliptical without any plan or any change in intensity--just the same thing every day hoping it will work better tomorrow. You can spot these people in big health clubs very easily (and they don't even wear rabbit ears).

I have HUGE respect for ANY athlete (athlete is defined as anyone that trains and uses their body for a living, so that includes pretty much everyone). I totally understand why people run marathons and heck, bike across the entire US from my volunteer stint on the RAAM and I give mad props to all of them. I personally will not be signing up any time soon though.

Don't worry, there are tons of stupid things that weight trainers do in the gym too! I tend to forget about it since the only gym I go to on occasion is at work and that is mostly cardio equipment. I do 95% of my sessions in my garage gym (aka the Xtreme Human Performance Center) and for cardio I primarily do KBs, some biking and now that summer is here more sprints, sledge hammer on the tire, push cars, etc.

I do feel the tide is turning and strength work is getting much more respect in the research community, but the reality is its much easier to study endurance training. I fully admit to falling in that camp too as part of my Monster Energy Drink study is using a bike ride to exhaustion because of previous literature (although not much) and it is easier to measure.

Yes, cardio (cardiorespiratory fitness) is very important! I actually believe that many strength athletes could benefit from more intelligent CRF work in their programs, even if strenght is their main goal. My buddy Aaron S from ND said it best, "it just helps to be 'ft'" I will save you a lecture about HRV and work capacity.

The reality is that this blog will never be a home for die hard endurance fans, and that is fine with me. I don't mean any disrespect to them, but I have to narrow the focus a bit to provide relevant info to the loyal readers

Hope that helps and thanks again for the feedback as most just unsubscribe without any comments or why; which makes it very hard for me to improve them. My goal long term is to make this a trusted home for athletic performance enhancement. I agree with Dr. Cobb when he said "it is actually UNnatrual to NOT be athletic"
Rock on
Mike N
PS
If anyone else has comments on this, post away in the comments section!

PPS
If you want some cool insider scoop from ACSM, sign up to my newsletter below

Saturday, May 31, 2008

ACSM Random Updates

Greetings from ACSM! Just waiting to fly back home soon and wanted to drop some random notes. I will have more updates coming in the next few weeks as I get threw over 40 pages of notes. Excellent information presented!

Here they are random, rapid fire style. More details soon
Inspiration Muscle Training
  • May work really really well. Poster from highly competitive cross country runners showed a shaving of 40 seconds off 5km times!! That is insane!
Central Pattern Generation
  • May be located in the spinal cord! The basic program for gait appears to be there too. Huge implications for spinal cord injury patients.
  • Gait has a normal variability to it on each step, we need to replicate this to obtain a normal gait again in rehab areas
  • Injuries will alter your gait (I see that all the time)
  • Interlimb coordination more important than INTRAlimb coordination
  • Rats with full spinal cord cut at around the top of the lumbar area can walk sideways and backwards on a treadmill on 2 legs with body weight support. No input from the brain--must be a FEED FORWARD mechanism on some level
Central vs Peripheral Fatigue
  • Studies, posters point to some of each
  • BCAAs don't seems to decrease central fatigue (although tyrosine seems to work)
Brain and Cognition and Exercise
  • Brain will adapt by increasing neurons
  • Brain actually increases in size and weight!! (Up to a limit)
  • Enriched environment is important, not just exercise---new movements, use of visual system
  • Exercise has an anti-depressant activity
Creatine
  • New mechanisms--potential cognition and ergogenic benefits
  • Full details soon
Random Tidbits
  • Vit D RDA most likely to increase dramatically soon
  • Women athletes should probably have ferritin iron test and Vit D test done
  • Talk by top protein researchers on protein and exercise--more info soon
  • Beta Alanine seems to work great in elite wrestlers (source--conversation on unpublished work)
  • NSAIDS and training may NOT interfere with each other

More soon!
Any questions in the meantime, post them here
Mike

Saturday, May 24, 2008

Anniversary, ACSM, Z Health/ KB Seminar and Food Clock Research

1 Year Anniversary of this Blog!

Just wanted to give a huge shout out to everyone that takes time out of their to read this blog. It is a true honor and privilege that you take time (which is a non renewable resource) to read what I have to say here. Thanks again I plan to have more good stuff coming up soon and a few longer in depth article as well as guest interviews. Be sure to check out the first blog entry HERE.

ACSM
I am off to present at the American College of Sports Medicine in Indianapolis this coming Wed-Sat at the end of May. I can't wait as it is an exercise geeks dream! Tons of great research being presented by the best of the best from all around the world. I will have updates here of course (may not happen until I am home though depending on internet access). If you are going to be there, drop me a line!

Z Health and Kettlebell Seminar in MN on Sunday June 8
I will be doing a 2 hours seminar with Fawn Friday, RKC, CFT, soon to be Z Health R Phase certified at the Press Gym in Little Canada on Sunday June 8 at noon. We will be covering a basic overview of KB exercise and Z Health principals too. It will be primarily geared towards Mixed Martial Arts (MMA) athletes, but others will learn stuff too. So if you want to learn how to move better, get stronger and reduce pain, drop me an email to sign up ASAP. Cost is only $35 if you sign up ahead of time. There is limited space, so sign up now.

Research Update
More bleeding edge research of course! Cool article below on how your body regulates sleep in coordinance with your eating schedule. They go on at the end to suggest a 16 hour fast may help those with jet lag. Not sure if I am willing to make that jump yet, but from personal experience I've had the best luck staying on the same eating schedule (usually a meal every 2-3 hours or so) on the NEW schedule and then some melatonin before bed.

So if I was flying to Germany, once I board the plane I set my watch to the new time. This usually entails staying up later (and thus eating more) on the flight there from Minnesota; but once I crash into bed early I feel pretty good the next day.

Does A 'Food Clock' In The Brain Supercede Circadian Rhythm?"

Submitted by News Account on 22 May 2008 - 6:00am. Neuroscience

In investigating the intricacies of the body’s biological rhythms, scientists at Beth Israel Deaconess Medical Center (BIDMC) have discovered the existence of a “food-related clock” which can supercede the “light-based” master clock that serves as the body’s primary timekeeper.

The findings, which appear in the May 23 issue of Science, help explain how animals adapt their circadian rhythms in order to avoid starvation, and suggest that by adjusting eating schedules, humans too can better cope with changes in time zones and nighttime schedules that leave them feeling groggy and jet-lagged.

“For a small mammal, finding food on a daily basis is a critical mission,” explains the study’s senior author Clifford Saper, MD, PhD, Chairman of the Department of Neurology at BIDMC and James Jackson Putnam Professor of Neurology at Harvard Medical School. “Even a few days of starvation is a common threat in natural environments and may result in the animal’s death.”

The suprachiasmatic nucleus (SCN), a group of cells in the brain’s hypothalamus, serves as the body’s primary biological clock. The SCN receives signals about the light-dark cycle through the visual system, and passes that information along to another cell group in the hypothalamus known as the dorsomedial nucleus (DMH). The DMH then organizes sleep-wake cycles, as well as cycles of activity, feeding and hormones.

“When food is readily available,” explains Saper, “this system works extremely well. Light signals from the retina help establish the animals’ circadian rhythms to the standard day-night cycle.” But, if food is not available during the normal wake period, animals need to be able to adapt to food that is available when they are ordinarily asleep.

In order to survive, animals appear to have developed a secondary “food-related” master clock. “This new timepiece enables animals to switch their sleep and wake schedules in order to maximize their opportunity of finding food,” notes Saper, who together with lead author Patrick Fuller, PhD, HMS Instructor in Neurology and coauthor Jun Lu, MD, PhD, HMS Assistant Professor of Neurology, set out to determine exactly where this clock was located.

“In addition to the oscillator cells in the SCN, there are other oscillator cells in the brain as well as in peripheral tissues like the stomach and liver that contribute to the development of animals’ food-based circadian rhythms,” says Saper. “Dissecting this large intertwined system posed a challenge.”

To overcome this obstacle, the authors used a genetically arrhythmic mouse in which one of the key genes for the biological clock, BMAL1, was disabled. They next placed the gene for BMAL1 into a viral vector which enabled them to restore a functional biological clock to only one spot in the brain at a time. Through this step-by-step analysis, the authors uncovered the feeding entrained clock in the DMH.

“We discovered that a single cycle of starvation followed by refeeding turns on the clock, so that it effectively overrides the suprachiasmatic nucleus and hijacks all of the circadian rhythms onto a new time zone that corresponds with food availability,” says Saper. And, he adds, the implications for travelers and shift workers are promising.

“Modern day humans may be able to use these findings in an adaptive way. If, for example, you are traveling from the U.S. to Japan, you are forced to adjust to an 11-hour time difference,” he notes. “Because the body’s biological clock can only shift a small amount each day, it takes the average person about a week to adjust to the new time zone. And, by then, it’s often time to turn around and come home.”

But, he adds, by adapting eating schedules, a traveler might be able to engage his second “feeding” clock and adjust more quickly to the new time zone.

“A period of fasting with no food at all for about 16 hours is enough to engage this new clock,” says Saper. “So, in this case, simply avoiding any food on the plane, and then eating as soon as you land, should help you to adjust – and avoid some of the uncomfortable feelings of jet lag.”

This research was supported by grants from the U.S. Public Health Service.