Thursday, June 12, 2008

June Research--Caffeine

WAKE UP! Ha! If you need help, here is the latest research on everyone's fav--caffeine!


Caffeine and other sympathomimetic stimulants: modes of action and effects on sports performance.

Conclusion: “Biochemical mechanisms that are consistent with more recent research findings, involving proteins such as DARPP-32 (dopamine and cAMP-regulated phosphoprotein), are helping to rationalize the molecular details of stimulant action in the central nervous system.”

Influence of caffeine ingestion on perceived mood states, concentration, and arousal levels during a 75-min university lecture.

Conclusion:” The results of this investigation show that university students report enhanced perceptual feelings of behavior and mood state when a low dose of caffeine is consumed 60 min prior to a 75-min academic lecture.”

Effects of caffeine on physiological responses to exercise: boys versus men.

Conclusion: “Metabolism is not affected by a moderate caffeine dose in children or adults. The same dose has a similar effect on blood pressure in both groups. The effect on HR was different, however, with a significant (p < .05) lowering in children in caffeinated versus placebo, with no adult effects.”

Methamphetamine self-administration and voluntary exercise have opposing effects on medial prefrontal cortex gliogenesis.

Conclusion: “Medial Prefrontal Cortex gliogenesis is vulnerable to psychostimulant abuse and physical activity with distinct underlying mechanisms. The susceptibility of Medial Prefrontal Cortex gliogenesis to even modest doses of methamphetamine could account for the pronounced pathology linked to psychostimulant abuse.”

Caffeine-induced changes in cardiovascular function during resistance training.

Conclusion: “To prevent elevated blood pressure and potential enhanced risk of heart disease, Caffeine intake should be monitored in at-risk men who participate in resistance training.”

Hydration and cognition: a critical review and recommendations for future research.

Conclusion: “Inclusion of a positive control condition, such as alcohol intake, a hypnotic drug, or other treatments known to produce adverse changes in cognitive performance should be included in such studies. To the extent possible, efforts to blind both volunteers and investigators should be an important consideration in study design.”

Caffeine effects on physical and cognitive performance during sustained operations.

Conclusion: “It was concluded that caffeine maintained both vigilance and physical performance during sustained operations that require periods of overnight wakefulness and restricted opportunities for daytime sleep.”

Immunoendocrine response to cycling following ingestion of caffeine and carbohydrate.

Conclusion: “Taken together, this suggests that coingestion of caffeine and carbohydrate has greater influence on immunoendocrine responses than neutrophil functional responses to prolonged exercise.”

Effect of caffeine supplementation on haematological and biochemical variables in elite soccer players under physical stress conditions.

Conclusion: “The pronounced increase in the white cell count in the group receiving caffeine appeared to be caused by greater muscle stress and consequently more intense endothelial and muscle cell injury. The use of caffeine may augment the risk of muscle damage in athletes.”

Well-trained endurance athletes' knowledge, insight, and experience of caffeine use.

Conclusion: “The most popular sources of caffeine information were self-experimentation (16%), fellow athletes (15%), magazines (13%), and journal articles (12%). Over half the athletes (53%) could not identify an amount of caffeine required to improve their triathlon performance. Mean (+/- standard deviation) suggested doses were 3.8 (+/- 3) mg/kg body weight. Few side effects associated with taking caffeine during exercise were reported.”

Caffeine-induced Ca(2+) release increases AMPK-dependent glucose uptake in rodent soleus muscle.

Conclusion: “SR Ca(2+)-activated CaMKK may control alpha(1)- activated protein kinase activation and be necessary for caffeine-stimulated glucose uptake in mouse soleus muscle.”

Caffeine, fluid-electrolyte balance, temperature regulation, and exercise-heat tolerance.

Conclusion: “Contrary to popular beliefs, proposes that caffeine consumption does not result in the following: (a) water-electrolyte imbalances or hyperthermia and (b) reduced exercise-heat tolerance.”

Evaluation of the effects of caffeine in the microcirculation and edema on thighs and buttocks using the orthogonal polarization spectral imaging and clinical parameters.

Conclusion: “Smoking as well as alcohol consumption and regular physical activity were not significantly related to the centimetrical reduction observed in treated thighs and hips.”